Symbol Name ID |
Ghr
growth hormone receptor MGI:95708 |
Darker colors indicate more annotations |
Human Phenotypes | Type II diabetes mellitus |
Abnormality of the endocrine system |
Decreased serum insulin-like growth factor 1 |
Anterior hypopituitarism |
Delayed puberty |
Delayed menarche |
Disease(s) Associated with GHR | ||||||
isolated growth hormone deficiency | ||||||
Laron syndrome | ||||||
type 2 diabetes mellitus |
Mouse Phenotypes | decreased pancreatic beta cell proliferation |
decreased pancreatic beta cell mass |
small pancreatic islets |
decreased pituitary gland weight |
decreased prostate gland ventral lobe weight |
abnormal seminal vesicle weight |
decreased seminal vesicle weight |
decreased corpora lutea number |
decreased mature ovarian follicle number |
impaired ovarian folliculogenesis |
decreased testis weight |
decreased insulin secretion |
decreased activity of thyroid gland |
abnormal ovary physiology |
abnormal testes secretion |
decreased testes secretion |
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Availability | Mouse Genotype | ||||||||||||||||
Ghrtm1Jjk/Ghrtm1Jjk | |||||||||||||||||
Ghrtm1.1Dlr/Ghrtm1.1Dlr Tg(Ins2-cre)25Mgn/0 (conditional) |
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Ghrtm1.1Dlr/Ghrtm1.1Dlr Tg(Ins2-cre)23Herr/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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